山楂叶提取物抗氧化作用

Abstract:

Objective  To study the effects that leaf of hawthorn restrain low-density lipopr otein C(LDL-C)oxidization.

Methods  This paper has chosen wister male rates as the object.While the rats were fed with high-fed stuff everyday, they were also fed with hawkthorn leaves, in high, medium and low doses respectively.After four weeks.obser vation, the levels of superox ide dismutase(SOD), glutathione-Px(GSH-Px)mid Vitamin E, malonyl dialdehyde(MDA)and fluoresceuce in LDLC were studied.

Results  The levels of SOD in each groups showed no significantly difference(P > 0.05), The levels of GSHPx in each leaf of hawthorn groups increased than that in high fat control group(P < 0.05).Vitamin E in high, medium and low doses groups showed significantly higher than that in high fat control group(P < 0.05).The levels of fluorescence in high doses groups, medium doses groups decreased compared with the level of high fat control group(P < 0.05).There were no significantly difference in each leaf of hawthorn groups and high fat control group(P > 0.05).

Conclusion  Leaf of hawthorn has the capacity of decreasing the content of fluorescence; decreasing the consume of Vitamin E in LDL-C; restraining LDL-C oxidization increase; and it has the capacity of anti-oxidation effects.

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