首页分享用于防止铅中毒的冠醚装饰硅光子技术

用于防止铅中毒的冠醚装饰硅光子技术

来源：花匠小妙招时间：2025-01-08 03:40

用于防止铅中毒的冠醚装饰硅光子技术

Luigi Ranno, Yong Zen Tan, Chi Siang Ong, Xin Guo, Khong Nee Koo, Xiang Li, Wanjun Wang, Samuel Serna, Chongyang Liu, Rusli, Callum G. Littlejohns, Graham T. Reed, Juejun Hu, Hong Wang, Jia Xu Brian Sia

摘要

铅（Pb2+）中毒是一个令人担忧、尚未得到解决的全球公共卫生危机，每年导致 100 万人死亡。然而，解决这一问题的公共政策却不尽人意。这项研究利用了冠醚的独特能力，冠醚可选择性地与特定离子结合。这项研究展示了高可升级硅光子学与冠醚胺通过费舍尔酯化以环境友好的方式进行共轭的协同整合。这就实现了一个集成光子平台，能够对各种离子进行操作中、高选择性和定量检测。这项研发打破了费歇尔酯化仅限于有机化合物的现有观念，促进了各种冠醚的后续胺共轭。该平台专门用于选择性检测 Pb2+，动态检测范围大，适用于现场样品。该平台与具有成本效益的制造技术相兼容，这表明集成光子传感器技术具有广泛应用的潜力，可防止社会上发生 Pb2+ 中毒事件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

摘要图片

Crown ether decorated silicon photonics for safeguarding against lead poisoning

Lead (Pb2+) toxification is a concerning, unaddressed global public health crisis that leads to 1 million deaths annually. Yet, public policies to address this issue have fallen short. This work harnesses the unique abilities of crown ethers, which selectively bind to specific ions. This study demonstrates the synergistic integration of highly-scalable silicon photonics, with crown ether amine conjugation via Fischer esterification in an environmentally-friendly fashion. This realizes an integrated photonic platform that enables the in-operando, highly-selective and quantitative detection of various ions. The development dispels the existing notion that Fischer esterification is restricted to organic compounds, facilitating the subsequent amine conjugation for various crown ethers. The presented platform is specifically engineered for selective Pb2+ detection, demonstrating a large dynamic detection range, and applicability to field samples. The compatibility of this platform with cost-effective manufacturing indicates the potential for pervasive implementation of the integrated photonic sensor technology to safeguard against societal Pb2+ poisoning.

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来源期刊

Nature Communications

期刊介绍： Nature Communications, an open-access journal, publishes high-quality research spanning all areas of the natural sciences. Papers featured in the journal showcase significant advances relevant to specialists in each respective field. With a 2-year impact factor of 16.6 (2022) and a median time of 8 days from submission to the first editorial decision, Nature Communications is committed to rapid dissemination of research findings. As a multidisciplinary journal, it welcomes contributions from biological, health, physical, chemical, Earth, social, mathematical, applied, and engineering sciences, aiming to highlight important breakthroughs within each domain.

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