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在柔性微图案表面装饰纳米光电传感器

来源：花匠小妙招时间：2025-01-08 03:40

在柔性微图案表面装饰纳米光电传感器

摘要

金或银等金属纳米粒子具有不同的形状、尺寸、表面特性和组合，可显示出局部表面等离子体共振等等离子特性，已被广泛用于生物液体中各种疾病标志物的床旁检测。本研究的重点是开发一种装饰在微图案柔性基底上的折射率（RI）传感器。采用软光刻技术将光盘表面的图案复制到柔性聚二甲基硅氧烷（PDMS）基底上。此外，还将等离子体金纳米粒子（AuNPs）固定在上面，以便在微图案表面注入等离子体信号。通过对平面、一维条纹图案表面和二维箱形图案表面进行比较分析，可以看出微图案表面在周围介质中存在分析物时，具有显示更大的等离子体信号变化的潜力。微图案基底的紫外-可见表征显示，当周围介质中存在不同浓度的生物分析物时，吸光度的变化更大，波长的偏移也更大。例如，当在该表面周围配置不同浓度的牛血清白蛋白（BSA）时，观察到吸光度明显增加，这表明该基底具有感应关键生物标记物的潜力。为了模拟和解释实验观察结果，我们进行了计算流体动力学（CFD）模拟。所提出的纳米微图案光质子传感器（n- $mu $ OS）显示了转化为具有显著更高的局部表面等离子体共振（LSPR）灵敏度的护理点设备的巨大潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Decoration of Nanoenabled Optoplasmonic Sensors on Flexible Micropatterned Surfaces

Metal nanoparticles, such as gold or silver, with varying shapes, sizes, surface properties, and assemblages, show plasmonic properties, such as localized surface plasmon resonance, which has been widely employed for the point-of-care sensing of various disease markers in the biofluids. The present study focuses on the development of a refractive index (RI) sensor decorated on a micropatterned flexible substrate. A soft lithography technique has been employed for the replica molding of the patterns present on a compact disk surface onto a flexible polydimethyl siloxane (PDMS) substrate. Furthermore, plasmonic gold nanoparticles (AuNPs) are immobilized on the same to infuse plasmonic signals on the micropatterned surface. A comparative analysis between the flat, 1-D stripe-patterned, and 2-D box-patterned surfaces shows the potential of the micropatterned surfaces in displaying a larger variation in the plasmonic signals in the presence of an analyte in the surrounding medium. The UV-visible characterization of the micropatterned substrate discloses a larger variation in the absorbance and a larger shift in the wavelength in the presence of different concentrations of bioanalytes in the surrounding media. For example, a significant increase in absorbance was observed when different bovine serum albumin (BSA) concentrations were dispensed in the surroundings of this surface, indicating the substrate’s potential to sense critical biomarkers. Computational fluid dynamic (CFD) simulations have been performed to emulate and explain the experimental observations. The proposed nanoenabled micropatterned optoplasmonic sensor (n-

$mu $

OS) shows a significant potential to translate into point-of-care devices with a significantly higher localized surface plasmon resonance (LSPR) sensitivity.

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来源期刊

IEEE Sensors Journal

期刊介绍： The fields of interest of the IEEE Sensors Journal are the theory, design , fabrication, manufacturing and applications of devices for sensing and transducing physical, chemical and biological phenomena, with emphasis on the electronics and physics aspect of sensors and integrated sensors-actuators. IEEE Sensors Journal deals with the following: -Sensor Phenomenology, Modelling, and Evaluation -Sensor Materials, Processing, and Fabrication -Chemical and Gas Sensors -Microfluidics and Biosensors -Optical Sensors -Physical Sensors: Temperature, Mechanical, Magnetic, and others -Acoustic and Ultrasonic Sensors -Sensor Packaging -Sensor Networks -Sensor Applications -Sensor Systems: Signals, Processing, and Interfaces -Actuators and Sensor Power Systems -Sensor Signal Processing for high precision and stability (amplification, filtering, linearization, modulation/demodulation) and under harsh conditions (EMC, radiation, humidity, temperature); energy consumption/harvesting -Sensor Data Processing (soft computing with sensor data, e.g., pattern recognition, machine learning, evolutionary computation; sensor data fusion, processing of wave e.g., electromagnetic and acoustic; and non-wave, e.g., chemical, gravity, particle, thermal, radiative and non-radiative sensor data, detection, estimation and classification based on sensor data) -Sensors in Industrial Practice

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