首页分享植物毒理学文献计量分析及其研究思路与方法评论

植物毒理学文献计量分析及其研究思路与方法评论

来源：花匠小妙招时间：2025-05-15 17:10

摘要:当前植物毒理学研究呈现快速发展的态势，研究人员在环境科学与植物科学主流学术期刊发表论文数量大幅增加，取得了许多重要成果。这些研究从不同角度和尺度揭示了污染物在植物体内的代谢动力学与生物有效性，污染物毒性效应的分子起始事件、关键生化反应、有害结局路径以及生物标志物筛选。然而，这些研究思路和方法上的相似性也带给我们一些疑惑：如何基于这些研究成果进一步找到本领域潜的关键科学问题？本文首先基于PubMed文献数据库对植物毒理学相关研究进行分析，得到了该研究领域近10年的基本发展态势。此外，还回顾了植物毒理学研究试验基础，从宏观和微观的角度解析了植物表型、生理生化和分子水平的研究思路和方法，也从应用角度阐述了研究降低污染物对植物毒性调控技术的注意事项，以期为研究者提供一些新的思考方向。

Abstract:Nowadays, the research advances in phytotoxicology are developing rapidly since many papers have been published in the mainstream academic journal of environmental science and plant science. Researchers have achieved lots of significant accomplishments. These researches revealed the metabolic kinetics and bioavailability of contaminants in plants with different perspectives and scales. Moreover, the molecular initiation event of toxic effects of contaminants, key biochemical response, detrimental effect pathway, and selection of biomarkers were investigated. However, the similarity of the research ideas and methods also brings doubts, that is, how to find the underlying scientific questions in this field through these current studies? Therefore, this review intends to (1) analyze the development of research on plant toxicology in this decade based on the PubMed literature database; (2) review the experimental basis of plant toxicology research; (3) explore the research designs and methods on plant phenotype, physiology, biochemistry, and molecular level from the macroscopic and microscopic perspectives; (4) explain the attentions involved in reducing the toxicity of contaminants to plants from the application perspectives. Overall, this study provides some new thinking orientations for investigating phytotoxicology in the future.

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