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环草石斛多酚成份及其生物活性

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环草石斛多酚成份及其生物活性

Polyphenols from Dendrobium loddigesii and their biological activities

王军

中山大学学报(自然科学版)(中英文) 2019年58卷第2期页码：96-102

DOI：10.13471/j.cnki.acta.snus.2019.02.012

纸质出版日期：2019，

网络出版日期：2019-3-25

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环草石斛多酚成份及其生物活性

李雪文 ; 陈慧萍 ; 何伟波 ; 杨文铃 ; 倪飞雨 ; 黃子雯 ; 胡海燕 ; 王军 ;

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Abstract

To study the polyphenols fromDendrobium loddigesiiand their biological activities, the 80% acetone extract fromD. loddigesiiwas isolated and purified by chromatography techniques; the structures of obtained compounds were identified with spectroscopic techniques; the antioxidative, α-glucosidase inhibitory and antiinflammatory activities of compounds were evaluated. Fifteen compounds were isolated and identified as chrysotoxol A (1), neoechinulin A (2), 3,6,9trihydroxy-3,4-dihydroanthracen-1(2H)-one (3), 4,4′=dihydroxyl-3,5-dimethoxylbibenzyl (4), naringenin (5), 5,4′-dihydroxy-7,3′,5′-trimethoxyflavanone (6), 5,7,4′-trihydroxy-3′,5′-dimethoxyflavanone (7), batatasin-III (8), 3,3′,5-trihydroxybibenzyl (9), trigonopol B (10), syringaresinol (11), 2,4,7-trihydroxyl-9,10dihydrophenanthrene (12), loddigesiinol B (13), loddigesiinol I (14), loddigesiinol J (15),respectively. Compounds1-11among them were isolated fromD. loddigesiifor the first time. The biological activities of compounds1-4, 6, 7and12were evaluated for the first time under trial conditions. It was reported for the first time that compounds1, 3and12had a strong antioxidant activity, compounds1and9showed a strong α-glucosidase inhibitory activity, and compounds1,12, 14and 15 had a strong anti-inflammatory activity.

译

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